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1.3 a thought experiment: extra reading & references

Course subject(s) Module 1. Old genes in a new environment

A classic observation that migrants adopt the lifestyle and consequentially the disease risk of the country they migrate to is found in a comparison of Indian family members of which some did and others did not migrate to the United Kingdom. 

  • Bhatnagar D, Anand IS, Durrington PN, Patel DJ, Wander GS, Mackness MI, Creed F, Tomenson B, Chandrashekhar Y, Winterbotham M, et al. Coronary risk factors in people from the Indian subcontinent living in west London and their siblings in India. Lancet. 1995;345:405-9.

 

Another example is from the breastcancer risk that rises when women from Asia migrate to the US:

  • Regina G. Ziegler, Robert N. Hoover, Malcolm C. Pike, Allan Hildesheim, Abraham M. Y. Nomura, Dee W. West, Anna H. Wu-Williams, Laurence N. Kolonel, Pamela L. Horn-Ross, Jeanne F. Rosenthal and Marianne B. HyerMigration Patterns and Breast Cancer Risk in Asian-American Women. JNCI J Natl Cancer Inst (1993) 85 (22): 1819-1827.
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