Welcome to module 3!
In module 2 we have seen that the performance of microorganisms is quantitatively described by biomass specific rates. In this week Sef Heijnen will use these rates to design a full scale aerobic PDO continuous fermentation. We will start with the cornerstone of this design: the process reaction. Sef will explain how the process reaction will be set-up using the Black Box kinetic model of the organism, which allows to calculate the biomass specific rates. Finally, we will discover how to make the PDO fermentation more sustainable.
You can find further updates of terminology, formulas and symbols for this week in the Course Info tab.
In the Best Practice, Mickel Jansen, senior scientist fermentation within the DSM biotechnology centre, will discuss industrial process development for succinic acid.
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The black box model and process reaction – lectures
- 3.1 The process reaction
- 3.2 Basics of the black box model
- 3.3 Energy consuming and energy producing products
- 3.4 A PDO black box model: experiments for parameter identification
- 3.5 Black box models: The PDO process reaction as function of mu
- 3.6 PDO continuous process design: calculation of inputs and outputs using the process reaction
- 3.7 Aerobic PDO process: improving sustainability
- Extra guest lecture balances
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Best Practice 3 – Industrial Process Development for Succinic Acid